Overview
Hormone and wellness care, in one place
Two women who both search “hormone therapy” could need very different things: a vaginal estrogen, a GLP-1 drug for weight, a thyroid workup, or FDA-approved estradiol plus progesterone. So this page covers a category of care rather than one procedure, and it is organized by the concern you walk in with, so you can decide what to raise with a clinician.
The longest sections cover hormone therapy for women, testosterone therapy for men and the GLP-1 drugs used for weight loss. Thyroid care, peptides and IV therapy get shorter treatment. Two Texas measures come up: a Texas Medical Board rule and a state law. On January 9, 2025, the Texas Medical Board’s rules for delegating cosmetic procedures took effect (Texas Medical Board). On September 1, 2025, Texas HB 3749 took effect; it covers elective IV therapy (Texas Legislature).
| Detail | Summary |
|---|---|
| Austin cost | No Austin price range for these therapies is listed on this site. The GLP-1 section gives what the manufacturers charge self-pay patients for Wegovy and Zepbound. |
| Prescriber’s first step | A medical history and tests that fit the therapy |
| Follow-up | Continuing; under testosterone guidance, the first check comes at 3 to 12 months and then once a year |
| Downtime | None, because treatment is ongoing |
Categories
The concerns this page covers
Perimenopause and menopause. Common symptoms are night sweats, hot flashes, vaginal dryness, painful sex and poor sleep. The FDA-approved choices are low-dose vaginal estrogen for genitourinary symptoms, or systemic estrogen, which is paired with a progestogen when you still have a uterus (The Menopause Society, 2022).
Low testosterone in men. According to the Endocrine Society, the diagnosis fits only a man who has signs and symptoms of deficiency along with levels that stay low, as a repeated morning fasting total testosterone test shows (Endocrine Society guideline, 2018).
Weight and metabolism. Semaglutide’s brand names are Ozempic for type 2 diabetes and Wegovy for weight; tirzepatide’s are Mounjaro for type 2 diabetes and Zepbound for weight (Ozempic label; Mounjaro label; Wegovy label; Zepbound label). FDA declared both shortages over in 2024 and 2025, which limits what compounding pharmacies may now make (FDA).
Peptides, IV drips and NAD+. Several peptides that wellness clinics sell were at one point put by FDA in Category 2 for compounding, the group it uses for substances that may present significant safety risks (FDA).
Thyroid. Hypothyroidism is treated with levothyroxine. A boxed warning on thyroid hormone labels says not to use these drugs for weight loss or obesity (Synthroid label).
Start by naming your own concern. Then ask the clinic which condition it plans to treat and which tests back up that diagnosis before anything is prescribed.
Decision
Matching symptoms to a first conversation
A rough guide for your first appointment:
| Your main symptoms | A good question to raise |
|---|---|
| Menopause-related hot flashes, night sweats or poor sleep | Menopause hormone therapy: systemic estrogen, plus a progestogen when you have a uterus |
| Painful sex or vaginal dryness after menopause | Low-dose vaginal estrogen, or another local option |
| Men with low libido, low energy or muscle loss | A testosterone evaluation: a repeated morning fasting test, plus a look for what is causing it |
| Weight gain | Medical weight loss: does your situation meet the labeled criteria for any FDA-approved GLP-1 drug? |
| Fatigue, feeling cold, weight gain | Thyroid testing |
More than one of these can be true at once. Ask the clinic which it will address first, and why.
Women
Hormone therapy for women
What the WHI found
Reported in 2002, the Women’s Health Initiative (WHI) trial randomized women aged 50 to 79 to a placebo or to conjugated equine estrogens with medroxyprogesterone acetate. The hormone group saw more coronary heart disease, invasive breast cancer, pulmonary embolism and stroke, along with fewer hip fractures and less colorectal cancer (Rossouw et al., JAMA 2002). Over 18 years of later follow-up, researchers found hormone therapy in the WHI trials was not associated with higher death rates from cancer, cardiovascular disease or any cause (Manson et al., JAMA 2017).
In its 2022 position statement, The Menopause Society separates women by timing. If a woman has no contraindications and is younger than 60, or less than 10 years past menopause onset, it judges the benefit-risk ratio favorable for preventing bone loss and for bothersome night sweats and hot flashes. If she starts after 60, or more than 10 years after menopause onset, it says the ratio appears less favorable, since her absolute risks of stroke, coronary heart disease, dementia and venous thromboembolism are greater (The Menopause Society, 2022).
In November 2025, FDA started removing boxed-warning language on breast cancer, cardiovascular disease and probable dementia from the labels of menopausal hormone therapy. The endometrial cancer boxed warning stays on systemic estrogen-alone products (FDA).
FDA-approved hormone therapy
- Systemic estradiol: examples include a spray (Evamist), gels (Estrogel, Divigel) and patches (Climara, Minivelle, Vivelle-Dot). According to The Menopause Society, risk depends on the type of hormone therapy, its route, dose, timing and duration, and on whether a progestogen is added (The Menopause Society, 2022).
- Micronized progesterone: Prometrium’s labeled dose for preventing endometrial hyperplasia, in a postmenopausal woman with a uterus who is on estrogen, is 200 mg taken at bedtime on 12 days of every 28-day cycle (Prometrium label). Estrogen labeling notes that adding a progestogen reduces the risk of endometrial hyperplasia, a condition that can come before endometrial cancer (Vivelle-Dot label).
- Vaginal estrogen for genitourinary syndrome of menopause: examples include Estring, Estrace cream, Imvexxy and Vagifem. If bothersome symptoms persist despite over-the-counter products, The Menopause Society’s recommendation is low-dose vaginal estrogen, or options such as oral ospemifene or vaginal DHEA (The Menopause Society, 2022).
- Combination products: examples include CombiPatch, which pairs estradiol with norethindrone acetate, and Bijuva, which pairs estradiol with progesterone.
The Vivelle-Dot label lists who should not use estrogen: women with liver disease or impairment, active or past blood clots, a stroke or heart attack now or in the past, estrogen-dependent cancer, breast cancer now or in the past, or genital bleeding that is abnormal and undiagnosed (Vivelle-Dot label).
Compounded bioidentical hormone therapy
A “bioidentical” hormone is one with the same chemistry as a hormone your body produces, and some FDA-approved products fit that definition. Prometrium is one: its label says its progesterone has a chemical structure identical to the progesterone a human ovary makes (Prometrium label). The more useful line to draw is between FDA-approved and compounded. Reviewing compounded bioidentical hormone therapy in 2020, the National Academies reported a lack of rigorous evidence, from well-designed clinical studies, for its safety and effectiveness (FDA summary of the NASEM report). If a clinic offers you a compounded product, ask what makes an FDA-approved one unsuitable for you.
Pellet therapy
Pellets go under the skin and release hormone over a period of months. Testopel is an FDA-approved testosterone pellet for men; its labeled dose is 150 mg to 450 mg, repeated every 3 to 6 months (Testopel label). Because that labeling is for males only, a woman offered a pellet should ask whether the product has FDA approval.
The 2019 Global Consensus Position Statement on testosterone for women recognizes one use backed by evidence: hypoactive sexual desire disorder in postmenopausal women, diagnosed after a formal assessment. It recommends against any testosterone product, injections and pellets among them, that raises levels past the normal range (supraphysiologic), and says compounded “bioidentical” testosterone cannot be recommended to treat low sexual desire (Global Consensus Position Statement, JCEM 2019). In a separate 2020 review, the National Academies urged FDA’s compounding advisory committee to consider all compounded bioidentical hormone pellets for the list it keeps of drugs that are difficult to compound (National Academies, 2020).
If pellets are recommended, ask the clinic what makes them better than FDA-approved pills, gels or patches, which of your hormone levels it plans to test, how it responds to a dose that runs too high, and how a dose can be lowered after the pellet is placed.
Men
Testosterone replacement therapy for men
Who qualifies
Here is the sequence the 2018 Endocrine Society guideline lays out (Endocrine Society guideline, 2018):
- Diagnose low testosterone only in men who have symptoms and signs of deficiency and whose levels are consistently low
- Confirm it with a morning fasting total testosterone test, repeated
- When total testosterone is near the bottom of the normal range, measure free testosterone
- After deficiency is confirmed, look for the cause
No single fixed cutoff of 300 ng/dL appears in the guideline. For standardized assays, it cites 264 ng/dL as the lower limit of normal in healthy young men who are not obese (Endocrine Society guideline, full text). Testopel’s label likewise calls for confirming the diagnosis with morning testosterone measured on two or more separate days (Testopel label). Before you get a prescription, ask whether the clinic repeats the test and looks for a cause.
According to the guideline, testosterone should not be started in men planning fertility soon, or in men with any of these: thrombophilia, uncontrolled heart failure, a stroke or heart attack within the last 6 months, untreated severe sleep apnea, severe lower urinary tract symptoms, an elevated hematocrit, a palpable prostate nodule, breast or prostate cancer, or a PSA above 4 ng/mL (above 3 ng/mL in higher-risk men) that has not had urologic evaluation (Endocrine Society guideline, 2018). The guideline also suggests not prescribing testosterone routinely to every man aged 65 or older (Endocrine Society guideline, full text).
The TRAVERSE trial
The TRAVERSE trial took 5,246 men between 45 and 80 years old with high heart risk or heart disease, hypogonadism symptoms, and two fasting testosterone readings below 300 ng/dL. They applied either a placebo gel or a 1.62% testosterone gel each day, for a mean of 21.7 months of treatment (Lincoff et al., NEJM 2023).
- Major cardiac events (nonfatal stroke, nonfatal heart attack or cardiovascular death) occurred in 7.0% of men on testosterone versus 7.3% on placebo, which made testosterone noninferior to placebo.
- Pulmonary embolism, acute kidney injury and atrial fibrillation were more frequent in the testosterone group.
In February 2025, FDA recommended adding the TRAVERSE results to every testosterone label and removing the boxed-warning language on increased cardiovascular risk, and it required warnings about blood pressure (FDA). FDA requested further label changes in June 2026, including removal of the limitation of use on age-related hypogonadism (FDA).
FDA-approved testosterone forms
- Injections: testosterone enanthate or cypionate; Xyosted, injected under the skin once a week (Xyosted label); and Aveed, a long-acting shot available only through a restricted REMS program, because it can cause pulmonary oil microembolism reactions (Aveed label)
- Gels: AndroGel is one example
- Oral capsules: Kyzatrex, Tlando, Jatenzo
- Nasal gel: Natesto
- Pellets: Testopel
Testosterone is classed as a Schedule III controlled substance (Testopel label). Prescribing or dispensing any controlled substance requires a federal registration (21 U.S.C. §822).
Monitoring
The Endocrine Society guideline calls for an evaluation 3 to 12 months after treatment begins, then every year. Hematocrit is measured at baseline, at 3 to 6 months and then yearly; if it rises above 54%, therapy is paused until it falls back to a safe level. For men who opt into prostate monitoring, a rectal exam and PSA follow 3 to 12 months after starting, and a urology referral is made for a confirmed PSA above 4 ng/mL or a PSA increase of more than 1.4 ng/mL within 12 months (Endocrine Society guideline, full text). Ask which of these tests the clinic will order, and how often.
Fertility
Men who plan to father children in the near term should not start testosterone, the Endocrine Society advises (Endocrine Society guideline, 2018). If children are in your plans, tell the clinic before anything is prescribed, and ask about a referral to a fertility specialist or urologist.
GLP-1
Medical weight loss and GLP-1 drugs
FDA-approved products
- Semaglutide: Ozempic carries approval for type 2 diabetes (Ozempic label). Wegovy, available as a weekly injection or a daily pill, carries approval for adults who have obesity, or who are overweight with one or more weight-related conditions, among other uses (Wegovy label).
- Tirzepatide: Mounjaro carries approval for type 2 diabetes (Mounjaro label). Zepbound carries approval for reducing excess body weight in adults who have obesity, or who are overweight with one or more weight-related conditions (Zepbound label).
What the main trials found
- STEP 1 (semaglutide 2.4 mg, NEJM 2021): the trial enrolled adults without diabetes with a BMI of 30 or higher, or 27 or higher with a weight-related condition. At 68 weeks, mean body weight had changed by -14.9% with semaglutide versus -2.4% with placebo (Wilding et al., NEJM 2021).
- SURMOUNT-1 (tirzepatide, NEJM 2022): at 72 weeks, mean weight change was -15.0% on 5 mg, -19.5% on 10 mg and -20.9% on 15 mg, compared with -3.1% on placebo. On those three doses, 85%, 89% and 91% of participants lost 5% or more of their body weight; on placebo, 35% did (Jastreboff et al., NEJM 2022).
In both trials, the most frequent side effects were gastrointestinal, and most were mild to moderate (Wilding et al.; Jastreboff et al.).
Compounded semaglutide and tirzepatide
FDA declared the tirzepatide shortage resolved on October 2, 2024, then confirmed it on December 19, 2024; the semaglutide shortage followed on February 21, 2025. For tirzepatide, the enforcement grace periods ran out on February 18, 2025 for 503A pharmacies and on March 19, 2025 for 503B outsourcing facilities. For semaglutide, they ran out on April 22, 2025 for 503A pharmacies and on May 22, 2025 for 503B facilities (FDA). A 503A pharmacy may still compound for an individual patient if the prescriber documents a significant difference for that person, but may not regularly or in inordinate amounts make what are essentially copies of the approved drug (FDA).
Compounded drugs reach the market without FDA review of their safety, effectiveness or quality. FDA has had reports of adverse events tied to compounded semaglutide and tirzepatide, including some that required hospitalization and some linked to dosing errors (FDA). FDA said in February 2026 that it plans to restrict GLP-1 ingredients in compounded drugs that it has not approved (FDA). If a clinic offers a compounded version, ask it to name the pharmacy that makes it and the patient-specific reason for using it.
Manufacturer self-pay prices
These are the self-pay prices the manufacturers publish, as checked on October 29, 2026. They are not what Austin clinics charge, and a clinic’s visit and lab fees are extra.
- Zepbound KwikPen (Lilly): 2.5 mg is $299 a month, 5 mg is $399, and 7.5 mg to 15 mg is $449, a higher-dose price that depends on refilling within 45 days. Vials are also $299 a month. The Lilly savings card runs out December 31, 2026 (Lilly).
- Wegovy (NovoCare): pens are $349 a month at doses up to 2.4 mg, and new self-pay patients get an introductory price of $199 a month on their first two fills of 0.25 mg and 0.5 mg. Wegovy HD 7.2 mg is $399 a month. Wegovy pills are $149 a month at 1.5 mg, $199 at 4 mg, and $299 at 9 mg or 25 mg. NovoCare plans to update its pricing after December 31, 2026 (NovoCare).
Safety
Wegovy and Zepbound must not be used by anyone who has MEN 2 or who has a personal or family history of medullary thyroid carcinoma, and each carries a boxed warning on thyroid C-cell tumors (Wegovy label; Zepbound label). Wegovy’s label also lists warnings for severe gastrointestinal reactions, acute pancreatitis, kidney injury from dehydration, gallbladder disease, low blood sugar, and pulmonary aspiration under deep sedation or general anesthesia. The label does not recommend Wegovy in severe gastroparesis and says to stop it 2 months or more before a planned pregnancy. If you are on it, let your anesthesia team or surgeon know before any procedure (Wegovy label).
In January 2026, FDA said its review found GLP-1 drugs did not raise the risk of suicidal behavior or thoughts, and it asked manufacturers to remove that warning from labels (FDA).
Peptides
Peptides
Which bulk ingredients can a 503A compounding pharmacy use? Only ingredients that have a USP or NF monograph, that are part of a drug FDA has approved, or that appear on FDA’s 503A bulks list. Until that list is finished, FDA allows the substances it has placed in Category 1 (FDA).
FDA uses Category 2 for substances it considers a possible significant safety risk. BPC-157, CJC-1295, TB-500, thymosin alpha-1, AOD-9604, GHK-Cu (injectable), melanotan II and Epitalon were once in that category before their nominators withdrew them. Ibutamoren and kisspeptin-10 are in Category 2. For several of these, FDA’s page points to limited safety data and possible immunogenicity, and for some, CJC-1295 and AOD-9604 among them, it reports serious adverse events (FDA). None of them is in Category 1 on FDA’s list as updated May 14, 2026 (FDA category list).
One FDA-approved peptide is Egrifta (tesamorelin), approved for reducing excess abdominal fat in adults who have HIV with lipodystrophy (Egrifta WR label).
For any peptide, ask whether it is an FDA-approved drug. If the answer is no, ask which pharmacy compounds it and on what grounds.
IV Therapy
IV therapy and NAD+
Jenifer’s Law, Texas HB 3749, was signed into law on June 20, 2025, with an effective date of September 1, 2025 (Texas Legislature). Under the law, elective IV therapy means IV fluids, nutrients, medications or blood that a patient requests to ease temporary discomfort or to improve temporary wellness. Prescribing or ordering can be delegated by a physician to a PA or APRN, and administration to an RN, PA or APRN, in each case under adequate physician supervision (HB 3749 text).
The evidence behind specific wellness drips, vitamin cocktails or NAD+ infusions is not graded on this page. Ask the clinic what the drip should do for you and what evidence backs that use, and ask who will place your IV, who will monitor you, and who the supervising physician is.
Thyroid
Thyroid
The standard treatment for hypothyroidism is levothyroxine. Thyroid hormone labels, levothyroxine (Synthroid) and liothyronine (T3, Cytomel) among them, have a boxed warning that these drugs are not for treating obesity or for weight loss. For people whose thyroid works normally, typical doses do not lower weight, and bigger doses can cause serious or even life-threatening toxicity (Synthroid label; Cytomel label). Per the levothyroxine label, overtreatment can also reduce bone mineral density and may cause arrhythmias, particularly in people with heart disease and in older patients (Synthroid label).
If a clinic suggests thyroid hormone, ask which of your test results show the need for it and how your dose will be tracked.
Texas Law
Texas rules to know
The Texas Medical Board’s rules on delegating nonsurgical medical cosmetic procedures, 22 TAC Chapter 169, Subchapter E, took effect January 9, 2025 (Texas Medical Board). They apply to cosmetic procedures such as injectables, not to hormone or GLP-1 prescribing generally. In short:
- Before any delegated procedure, the patient must have a practitioner-patient relationship established by a physician, or by a PA or APRN acting under the physician’s delegation (22 TAC §169.26).
- While the procedure is under way, a physician, PA or APRN has to be on site, or immediately available for emergency consultation (22 TAC §169.26).
- Delegation is made by a written order that names the delegating physician and covers screening of patients, appropriate care, and what to do about complications and emergencies (22 TAC §169.27). The person performing the procedure must also sign and date a written protocol (22 TAC §169.26).
- The delegating physician’s name and Texas license number must be displayed in every public area and treatment room (22 TAC §169.28).
Elective IV therapy falls under HB 3749, covered in the IV section above (HB 3749 text).
Before a cosmetic injection or IV drip at an Austin wellness clinic, confirm these three things:
- You can see the delegating physician’s name and Texas license number posted (22 TAC §169.28)
- A physician, or a PA or APRN acting under the physician’s delegation, has established a practitioner-patient relationship with you before any delegated procedure (22 TAC §169.26)
- The person prescribing testosterone has a federal controlled-substance registration (21 U.S.C. §822)
What to Expect
The consultation, labs and monitoring
History. You can expect to be asked about sleep apnea, heart and clotting history, any family history of hormone-sensitive cancers, pregnancy plans, the medications you take now, and your medical history.
Tests. Which tests you get depends on the therapy. When a man is considering testosterone, the Endocrine Society recommends looking for the cause, measuring free testosterone if total testosterone sits near the low end of normal, and repeating a morning fasting total testosterone test. Hematocrit and PSA are also among the checks it lists before treatment begins (Endocrine Society guideline, 2018). Before prescribing a GLP-1 drug, the clinic should ask you about MEN 2 and medullary thyroid carcinoma (Wegovy label).
Monitoring. Testosterone patients are evaluated at 3 to 12 months and then every year, with hematocrit measured at baseline, at 3 to 6 months and then yearly (Endocrine Society guideline, full text). Women on menopause hormone therapy have the benefits and risks of staying on it reevaluated periodically (The Menopause Society, 2022). The Wegovy injection dose goes up every 4 weeks until it reaches maintenance (Wegovy label).
At any clinic, ask which tests will be ordered before a prescription and when the results will be reviewed with you.
Austin Pricing
Austin pricing
This page publishes no Austin price range for testosterone, hormone therapy, peptides, IV therapy or GLP-1 programs. Its only prices are the self-pay prices Lilly and Novo Nordisk publish for Zepbound and Wegovy, listed in the GLP-1 section (Lilly; NovoCare). Ask any clinic for its full price in writing, including the medication, labs and visits, and ask whether a contract is required.
How to Choose
Choosing a provider: what to check
Product sourcing.
- GLP-1 drugs: is it compounded or FDA-approved? If it is compounded, what patient-specific reason has been documented (FDA)?
- Hormones: is it compounded or FDA-approved? If it is compounded, what rules out an FDA-approved product for you (FDA summary of the NASEM report)?
- Peptides: is it an FDA-approved product, and if it is not, does it sit in FDA’s Category 1 (FDA category list)?
Testing and monitoring.
- Testosterone: does the diagnosis rest on a repeated morning fasting test and a look for the cause (Endocrine Society guideline, 2018)?
- Testosterone: will hematocrit be checked at baseline, again at 3 to 6 months, and every year (Endocrine Society guideline, full text)?
- GLP-1 drugs: will you be asked about MEN 2 and medullary thyroid carcinoma (Wegovy label)?
Credentials.
- Is the delegating physician’s name and Texas license number on display (22 TAC §169.28)?
- Before a delegated cosmetic procedure, does a physician, or a PA or APRN under the physician’s delegation, establish a practitioner-patient relationship with you (22 TAC §169.26)?
- For IV therapy, who is the supervising physician (HB 3749 text)?
Warning signs.
- Prescribing with no medical history or tests
- Thyroid hormone sold as a weight-loss treatment (Synthroid label)
- Peptides such as BPC-157 on the menu that are not FDA-approved and not in FDA’s Category 1 (FDA category list)
- Compounded semaglutide or tirzepatide with no patient-specific reason documented (FDA)
- Pellets offered to women without any mention of FDA-approved options (Global Consensus Position Statement, JCEM 2019)
- Testosterone prescribed after one test, without a repeat or a search for the cause (Endocrine Society guideline, 2018)
- No posted name or Texas license number for the delegating physician (22 TAC §169.28)
Treatment Areas